Cryoelectron tomography of radial spokes in cilia and flagella

  title={Cryoelectron tomography of radial spokes in cilia and flagella},
  author={Gaia Pigino and Khanh Huy Bui and Aditi Maheshwari and Pietro Lupetti and Dennis R. Diener and Takashi Ishikawa},
  booktitle={The Journal of cell biology},
Radial spokes (RSs) are ubiquitous components in the 9 + 2 axoneme thought to be mechanochemical transducers involved in local control of dynein-driven microtubule sliding. They are composed of >23 polypeptides, whose interactions and placement must be deciphered to understand RS function. In this paper, we show the detailed three-dimensional (3D) structure of RS in situ in Chlamydomonas reinhardtii flagella and Tetrahymena thermophila cilia that we obtained using cryoelectron tomography (cryo… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS