Cryo-electron tomography of microtubule-kinesin motor complexes.

  title={Cryo-electron tomography of microtubule-kinesin motor complexes.},
  author={Julia Cope and Susan P Gilbert and Ivan Rayment and David N. Mastronarde and Andreas H Hoenger},
  journal={Journal of structural biology},
  volume={170 2},
Microtubules complexed with molecular motors of the kinesin family or non-motor microtubule associated proteins (MAPs) such as tau or EB1 have been the subject of cryo-electron microcopy based 3-D studies for several years. Most of these studies that targeted complexes with intact microtubules have been carried out by helical 3-D reconstruction, while few were analyzed by single particle approaches or from 2-D crystalline arrays. Helical reconstruction of microtubule-MAP or motor complexes has… CONTINUE READING
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Microtubule binding patterns of the reverse kinesin motor Ncd reveal a minusend directed power stroke

  • T. G. Wendt, N. Volkmann, K. N. Goldie, J. Müller, E. Mandelkow, A. Hoenger
  • EMBO J
  • 2002
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