Cryo-electron tomography of microtubule-kinesin motor complexes.

@article{Cope2010CryoelectronTO,
  title={Cryo-electron tomography of microtubule-kinesin motor complexes.},
  author={Julia Cope and Susan P Gilbert and Ivan Rayment and David N. Mastronarde and Andreas H Hoenger},
  journal={Journal of structural biology},
  year={2010},
  volume={170 2},
  pages={257-65}
}
Microtubules complexed with molecular motors of the kinesin family or non-motor microtubule associated proteins (MAPs) such as tau or EB1 have been the subject of cryo-electron microcopy based 3-D studies for several years. Most of these studies that targeted complexes with intact microtubules have been carried out by helical 3-D reconstruction, while few were analyzed by single particle approaches or from 2-D crystalline arrays. Helical reconstruction of microtubule-MAP or motor complexes has… CONTINUE READING
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Microtubule binding patterns of the reverse kinesin motor Ncd reveal a minusend directed power stroke

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