Crucial role of milk-borne insulin in the development of pancreatic amylase at the onset of weaning in rats.

@article{Kinouchi1998CrucialRO,
  title={Crucial role of milk-borne insulin in the development of pancreatic amylase at the onset of weaning in rats.},
  author={Toshi Kinouchi and Kyoko Koizumi and Tamotsu Kuwata and Takaji Yajima},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={1998},
  volume={275 6},
  pages={R1958-R1967}
}
The development of pancreatic amylase activity was examined in rats fed in regular cages or in special cages, designed so the pups could not reach solid food to prevent weaning. In both groups, the amylase activity in zymogen granules increased in rat pups aged 14 days, peaked at 18 days, and thereafter remained at a 1.6-fold higher level than at 14 days of age. An increase in the plasma concentration of immunoreactive insulin preceded the increase of amylase activity, whereas the plasma… CONTINUE READING