Crucial Role of Calcium-Sensing Receptor Activation in Cardiac Injury of Diabetic Rats

@inproceedings{Qi2013CrucialRO,
  title={Crucial Role of Calcium-Sensing Receptor Activation in Cardiac Injury of Diabetic Rats},
  author={Hanping Qi and Yonggang Cao and Wei Huang and Yang Liu and Ye Wang and Lei Li and Lijuan Liu and Zhong Ji and Hongli Sun},
  booktitle={PloS one},
  year={2013}
}
Cardiac injury is a common pathological change frequently accompanied by diabetes mellitus. Recently, some evidence indicated that calcium-sensing receptor (CaSR) expressed in the cardiac tissue. However, the functional role of CaSR in diabetic cardiac injury remains unclear. The present study was designed to investigate the relationship between CaSR activation and diabetes-induced cardiac injury. Diabetic model was successfully established by administration of streptozotocin (STZ) in vivo, and… CONTINUE READING

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