Crosstalk between the microbiome and cancer cells by quorum sensing peptides

@article{Wynendaele2015CrosstalkBT,
  title={Crosstalk between the microbiome and cancer cells by quorum sensing peptides},
  author={E. Wynendaele and F. Verbeke and M. D'Hondt and A. Hendrix and C. Wiele and C. Burvenich and K. Peremans and O. Wever and M. Bracke and B. Spiegeleer},
  journal={Peptides},
  year={2015},
  volume={64},
  pages={40-48}
}
To date, the precise role of the human microbiome in health and disease states remains largely undefined. Complex and selective crosstalk systems between the microbiome and mammalian cells are also not yet reported. Research up till now mainly focused on bacterial synthesis of virulence factors, reactive oxygen/nitrogen species (ROS/RNS) and hydrogen sulphide, as well as on the activation of exogenous mutagen precursors by intestinal bacteria. We discovered that certain quorum sensing peptides… Expand
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