Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis

@article{Cadwell2016CrosstalkBA,
  title={Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis},
  author={Ken Cadwell},
  journal={Nature Reviews Immunology},
  year={2016},
  volume={16},
  pages={661-675}
}
Autophagy has broad functions in immunity, ranging from cell-autonomous defence to coordination of complex multicellular immune responses. The successful resolution of infection and avoidance of autoimmunity necessitates efficient and timely communication between autophagy and pathways that sense the immune environment. The recent literature indicates that a variety of immune mediators induce or repress autophagy. It is also becoming increasingly clear that immune signalling cascades are… CONTINUE READING
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