Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation

@inproceedings{Ma2016CrosstalkBW,
  title={Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation},
  author={Bin Ma and Michael O Hottiger},
  booktitle={Front. Immunol.},
  year={2016}
}
Besides its important role in embryonic development and homeostatic self-renewal in adult tissues, Wnt/β-catenin signaling exerts both anti-inflammatory and proinflammatory functions. This is, at least partially, due to either repressing or enhancing the NF-κB pathway. Similarly, the NF-κB pathway either positively or negatively regulates Wnt/β-catenin signaling. Different components of the two pathways are involved in this crosstalk, forming a complex regulatory network. This review summarizes… CONTINUE READING
Highly Cited
This paper has 515 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.
28 Citations
92 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

516 Citations

0200400201620172018
Citations per Year
Semantic Scholar estimates that this publication has 516 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 92 references

a key role in inflammatory diseases

  • PP Tak, Firestein GS. NF-kappaB
  • J Clin Invest
  • 2001
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…