Crossover study of (99m)Tc-TRODAT-1 SPECT and (18)F-FDOPA PET in Parkinson's disease patients.

@article{Huang2003CrossoverSO,
  title={Crossover study of (99m)Tc-TRODAT-1 SPECT and (18)F-FDOPA PET in Parkinson's disease patients.},
  author={Wen-Sheng Huang and Yung-Hsiao Chiang and J C Lin and Yuan-Hwa Chou and Cheng-Yi Cheng and Ren-Shyan Liu},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2003},
  volume={44 7},
  pages={999-1005}
}
UNLABELLED 99mTc-TRODAT-1 ([2-[[2-[[[3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3,2,1]oct-2-yl]methyl](2-mercaptoethyl)amino]ethyl]amino]ethanethiolato(3-)-N2,N2',S2,S2']oxo-[1R-(exo-exo)]) is a potential agent for dopamine transporter (DAT) SPECT, whereas 6-(18)F-fluoro-L-dopa ((18)F-FDOPA) PET has been used for the quantitative assessment of presynaptic nigrostriatal dopaminergic function. The current study investigated the relationship between the 2 imaging modalities in evaluating patients… CONTINUE READING
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