Crosslinking of human lens 9 kDa gammaD-crystallin fragment in vitro and in vivo.

@article{Srivastava2003CrosslinkingOH,
  title={Crosslinking of human lens 9 kDa gammaD-crystallin fragment in vitro and in vivo.},
  author={Om P. Srivastava and Kiran Srivastava},
  journal={Molecular vision},
  year={2003},
  volume={9},
  pages={644-56}
}
PURPOSE [corrected] The aims of this study were to determine in vitro crosslinking of a 9 kDa gammaD-crystallin fragment alone and with alpha-, beta-, or gamma-crystallins, the existence of covalent multimers of the polypeptide in vivo, and posttranslational modifications in the three isoforms of the polypeptide. METHODS A mixture of crystallin fragments (3-14 kDa), a 9 kDa gammaD-crystallin polypeptide or the polypeptide and individual alpha-, beta-, or gamma-crystallins, were incubated at… CONTINUE READING