Crosslinking of decellularized porcine heart valve matrix by procyanidins.

  title={Crosslinking of decellularized porcine heart valve matrix by procyanidins.},
  author={Wanyin Zhai and Jiang Chang and Kaili Lin and Junyin Wang and Qiang Zhao and Xiaoning Sun},
  volume={27 19},
Heart valve diseases have a significant high mortality, and the valve replacement using glutaraldehyde crosslinked porcine heart valves is one of the main curing techniques. But its application is limited due to poor durability, calcification of the valves and immunogenic reactions. The aim of this study was to evaluate the crosslinking effect of procyanidins on porcine heart valve matrix. After crosslinking of the decellularized porcine aortic heart valves by procyanidins, the tensile strength… CONTINUE READING

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