Crosslinked multilamellar liposomes for controlled delivery of anticancer drugs.

@article{Joo2013CrosslinkedML,
  title={Crosslinked multilamellar liposomes for controlled delivery of anticancer drugs.},
  author={Kye-Il Joo and Liang Xiao and Shuanglong Liu and Yarong Liu and Chi-Lin Lee and Peter Selby Conti and Michael K. K. Wong and Zibo Li and Pin Wang},
  journal={Biomaterials},
  year={2013},
  volume={34 12},
  pages={
          3098-109
        }
}
Liposomes constitute one of the most popular nanocarriers for the delivery of cancer therapeutics. However, since their potency is limited by incomplete drug release and inherent instability in the presence of serum components, their poor delivery occurs in certain circumstances. In this study, we address these shortcomings and demonstrate an alternative liposomal formulation, termed crosslinked multilamellar liposome (CML). With its properties of improved sustainable drug release kinetics and… CONTINUE READING
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