Cross-talk between L-type Ca2+ channels and mitochondria.

  title={Cross-talk between L-type Ca2+ channels and mitochondria.},
  author={Helena M. Viola and Livia C. Hool},
  journal={Clinical and experimental pharmacology & physiology},
  volume={37 2},
1. Calcium is necessary for myocardial function, including contraction and maintenance of cardiac output. Calcium is also necessary for myocardial energetics and production of ATP by mitochondria, but the mechanisms for calcium regulation by mitochondria are still not fully resolved. 2. The cytoskeleton plays an important role in maintaining a cell's integrity. It is now recognized that cytoskeletal proteins can also assist in the transmission of signals from the plasma membrane to… CONTINUE READING
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The role of calcium and the L-type calcium channel in pathological remodeling of the heart

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