Cross-study analysis of gene expression data for intermediate neuroblastoma identifies two biological subtypes

@article{Warnat2006CrossstudyAO,
  title={Cross-study analysis of gene expression data for intermediate neuroblastoma identifies two biological subtypes},
  author={Patrick Warnat and Andr{\'e} Oberthuer and Matthias Hermann Fischer and Frank Westermann and Roland Eils and Benedikt Brors},
  journal={BMC Cancer},
  year={2006},
  volume={7},
  pages={89 - 89}
}
Neuroblastoma patients show heterogeneous clinical courses ranging from life-threatening progression to spontaneous regression. Recently, gene expression profiles of neuroblastoma tumours were associated with clinically different phenotypes. However, such data is still rare for important patient subgroups, such as patients with MYCN non-amplified advanced stage disease. Prediction of the individual course of disease and optimal therapy selection in this cohort is challenging. Additional… CONTINUE READING
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