Cross-species surface display of functional spirochetal lipoproteins by recombinant Borrelia burgdorferi.

@article{Zckert2004CrossspeciesSD,
  title={Cross-species surface display of functional spirochetal lipoproteins by recombinant Borrelia burgdorferi.},
  author={Wolfram R. Z{\"u}ckert and Jill E Lloyd and Philip E Stewart and Patricia A Rosa and Alan G Barbour},
  journal={Infection and immunity},
  year={2004},
  volume={72 3},
  pages={1463-9}
}
Surface-exposed lipoproteins of relapsing fever (RF) and Lyme borreliosis Borrelia spirochetes mediate certain interactions of the bacteria with their arthropod and vertebrate hosts. RF spirochetes such as Borrelia hermsii serially evade the host's antibody response by multiphasic antigenic variation of Vsp and Vlp proteins. Furthermore, the expression of Vsp1 and Vsp2 by Borrelia turicatae is associated with neurotropism and higher blood densities, respectively. In contrast to RF Borrelia… CONTINUE READING
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