Cross-species models of OCD spectrum disorders

@article{Boulougouris2009CrossspeciesMO,
  title={Cross-species models of OCD spectrum disorders},
  author={Vasileios Boulougouris and Samuel Robin Chamberlain and Trevor W. Robbins},
  journal={Psychiatry Research},
  year={2009},
  volume={170},
  pages={15-21}
}
Several axis-I neuropsychiatric disorders are characterised by repetitive motor habits suggestive of underlying inhibitory dyscontrol, and may constitute members of a putative obsessive-compulsive (OC) spectrum. Notable examples include obsessive-compulsive disorder (OCD) and trichotillomania (repetitive hair-pulling). Multiple tiers of evidence link these conditions with underlying dysregulation of fronto-striatal circuitry and monoamine systems. These abnormalities represent key targets for… CONTINUE READING

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