Cross-species models of OCD spectrum disorders

  title={Cross-species models of OCD spectrum disorders},
  author={Vasileios Boulougouris and Samuel Robin Chamberlain and Trevor W. Robbins},
  journal={Psychiatry Research},
Several axis-I neuropsychiatric disorders are characterised by repetitive motor habits suggestive of underlying inhibitory dyscontrol, and may constitute members of a putative obsessive-compulsive (OC) spectrum. Notable examples include obsessive-compulsive disorder (OCD) and trichotillomania (repetitive hair-pulling). Multiple tiers of evidence link these conditions with underlying dysregulation of fronto-striatal circuitry and monoamine systems. These abnormalities represent key targets for… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 22 extracted citations

Combined Effects of Alcohol and Stress during the Prenatal Period on Behavior in Adult Mice

Neuroscience and Behavioral Physiology • 2012
View 8 Excerpts
Highly Influenced

Predictive validity of a non-induced mouse model of compulsive-like behavior

M. Greene-Schloessera, E. A. Van der Zeeb, +6 authors A. Bult-Itoa
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 96 references

A cross-sectional study on compulsive behaviour (stable vices) in horses.

Equine veterinary journal. Supplement • 1998
View 5 Excerpts
Highly Influenced

Psychogenic alopecia in a cat: response to clomipramine.

Journal of the South African Veterinary Association • 1998
View 4 Excerpts
Highly Influenced

Social and husbandry factors affecting the prevalence and severity of barbering (‘whisker trimming’) by laboratory mice

J. P. Garner, B. Dufour, L. E. Gregg, S. M. Weisker, J. A. Mench
Applied Animal Behaviour Science • 2004
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…