Cross-sex hormone administration changes pain in transsexual women and men

  title={Cross-sex hormone administration changes pain in transsexual women and men},
  author={Anna Maria Aloisi and Valeria Bachiocco and Antonietta Costantino and Rita Stefani and Ilaria Ceccarelli and Alessandro Bertaccini and Maria Cristina Meriggiola},

Is it All about Sex? Acupuncture for the Treatment of Pain from a Biological and Gender Perspective

  • I. LundT. Lundeberg
  • Medicine, Psychology
    Acupuncture in medicine : journal of the British Medical Acupuncture Society
  • 2008
When assessing the outcome of pharmacological and non-pharmacological therapies in pain treatment, the factors of gender and sex should be taken into account as the response to an intervention may differ.

Menopause affects pain depending on pain type and characteristics

Preliminary data is provided suggesting that menopause can affect pain depending on the painful condition experienced by the woman, which underlines the different interactions ofMenopause-related events with body structures involved in pain.

Gender aspects of the pain syndrome

Additional studies will be required to clarify the mechanisms that determine sex differences in pain responses in order to provide adequate pain relief, according to the patient’s needs.

Sex-based differences in pain perception and treatment.

Greater understanding of the factors that commonly and differentially affect the disparity in pain perception, as well as analgesic response, are beginning to illuminate research targets and promising areas of therapeutic intervention for improved pain management.

A Prospective Study on Sexual Function and Mood in Female-to-Male Transsexuals During Testosterone Administration and After Sex Reassignment Surgery

A positive effect of testosterone treatment on sexual function and mood in female-to-male transsexual subjects is suggested.

Relationship of female sex hormones with pain perception: focus on estrogens.

Old and new literature is summarized to evaluate data on pain and its modulation by gonadal hormones, particularly estrogens andipheral and central targets of these hormones are discussed with the aim of renewing interest in important aspects of estrogenic functions and their interactions with pain processes.

Sex-Gender Differences in Irritable Bowel Syndrome

A more sex-gender-oriented approach in the medical care setting could improve understanding of heterogeneous patients suffering from IBS and an individualized and multicomponent approach including sex and gender issues might help improve the treatment of IBS.

Pain: sex differences and implications for treatment.

  • J. Manson
  • Medicine, Biology
    Metabolism: clinical and experimental
  • 2010



Migraine prevalence in male to female transsexuals on hormone therapy

Male to female transsexuals (MFTs) are assessed using antiandrogens to suppress male sex characteristics and estrogens to induce female sex characteristics for the presence of headache to understand the relationship between migraine and sex hormones.

Hormone Treatment of the Adult Transsexual Patient

  • L. Gooren
  • Medicine, Biology
    Hormone Research in Paediatrics
  • 2005
The goal of treatment in female-to-male transsexuals is to induce virilization, including a male pattern of sexual hair, a male voice and male physical contours, and to stop menses.

Sexual and Physical Health After Sex Reassignment Surgery

After SRS, the transsexual person's expectations were met at an emotional and social level, but less so at the physical and sexual level even though a large number of transsexuals (80%) reported improvement of their sexuality.

Sex differences in pain perception.

Endocrine intervention for transsexuals

This review discusses predisposing factors to transsexualism, and the diagnosis, assessment and hormone treatment of transsexual patients, and discusses the risks and organ-specific effects of crosssex hormone treatment.

Sex differences in pain and analgesia: the role of gonadal hormones

Sex hormones, central nervous system and pain

Gonadal Hormones and Sex Differences in Pain Reactivity

  • A. Aloisi
  • Medicine
    The Clinical journal of pain
  • 2003
The morphologic and functional aspects of gonadal hormone systems and the relations between gonadal hormones and pain circuits are examined to identify areas deserving of increased attention in elucidating the endocrine mechanisms that contribute to abnormal pain states.

Masculinity, Femininity, and Transsexualism

The study revealed that transsexualism does not imply a simple inversion of sex-role patterns: transsexuals differ not only from nontranssexual individuals of the same anatomical sex but also from those of the opposite sex.