Cross-sensitization between testosterone and cocaine in adolescent and adult rats

@article{Engi2015CrosssensitizationBT,
  title={Cross-sensitization between testosterone and cocaine in adolescent and adult rats},
  author={Sheila Antonagi Engi and F{\'a}bio Cardoso Cruz and Carlos C Crestani and Cle{\'o}patra da Silva Planeta},
  journal={International Journal of Developmental Neuroscience},
  year={2015},
  volume={46},
  pages={33-37}
}
Cocaine and anabolic-androgenic steroids are substances commonly co-abused. The use of anabolic steroids and cocaine has increased among adolescents. However, few studies investigated the consequences of the interaction between anabolic-androgenic steroids in animals' model of adolescence. We examined the effects of acute and repeated testosterone administration on cocaine-induced locomotor activity in adult and adolescent rats. Rats received ten once-daily subcutaneous (s.c.) injections of… CONTINUE READING
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