Cross-sectional study on prevalences of psychiatric disorders in mutation carriers of Huntington's disease compared with mutation-negative first-degree relatives.

@article{Duijn2008CrosssectionalSO,
  title={Cross-sectional study on prevalences of psychiatric disorders in mutation carriers of Huntington's disease compared with mutation-negative first-degree relatives.},
  author={Erik van Duijn and Elisabeth M Kingma and Reinier Timman and Frans G Zitman and Aad Tibben and Raymund A. C. Roos and Rose C. van der Mast},
  journal={The Journal of clinical psychiatry},
  year={2008},
  volume={69 11},
  pages={1804-10}
}
OBJECTIVE To investigate the prevalences of formal DSM-IV diagnoses in pre-motor- symptomatic and motor-symptomatic mutation carriers at different stages of Huntington's disease compared to a control group of first-degree noncarrier relatives and the general population. METHOD Between May 2004 and August 2006, 154 verified mutation carriers and 56 verified noncarriers were recruited from the outpatient clinics of the Neurology and Clinical Genetics departments of Leiden University Medical… CONTINUE READING