Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study.

@article{Hamburg2008CrosssectionalRO,
  title={Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study.},
  author={Naomi M. Hamburg and Michelle J. Keyes and Martin G. Larson and Ramachandran S. Vasan and Renate B. Schnabel and Moira McAllister Pryde and Gary F. Mitchell and Jacob Sheffy and Joseph A. Vita and Emelia J Benjamin},
  journal={Circulation},
  year={2008},
  volume={117 19},
  pages={2467-74}
}
BACKGROUND Digital pulse amplitude augmentation in response to hyperemia is a novel measure of peripheral vasodilator function that depends partially on endothelium-derived nitric oxide. Baseline digital pulse amplitude reflects local peripheral arterial tone. The relation of digital pulse amplitude and digital hyperemic response to cardiovascular risk factors in the community is unknown. METHODS AND RESULTS Using a fingertip peripheral arterial tonometry (PAT) device, we measured digital… CONTINUE READING
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Endothelial dysfunction in atherosclerosis: mechanisms of impaired nitric oxide bioactivity

  • NM Hamburg, JA Vita
  • Loscalzo J, ed. Molecular Mechanisms of…
  • 2006

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