Cross-resistance patterns related to glutathione metabolism in primary human renal cell carcinoma

Abstract

In 59 cases of primary human renal cell carcinoma (RCC), cross-resistance and collateral susceptibility patterns were determined in an MTT microculture assay. Concomitantly, the glutathione (GSH) content and the enzymatic activity of γ-glutamyl transpeptidase (GGT) were measured as distinct resistance characteristics. Resistance or chemoresponse towards… (More)
DOI: 10.1007/BF00368184

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