Cross-reactivity of the CEDIA buprenorphine assay with opiates: an Austrian phenomenon?

  title={Cross-reactivity of the CEDIA buprenorphine assay with opiates: an Austrian phenomenon?},
  author={Marion Pavlic and Kathrin Libiseller and Petra Grubwieser and Walter Rabl},
  journal={International Journal of Legal Medicine},
When testing the Microgenics CEDIA assay for immunological buprenorphine analysis, cross-reactivity between the buprenorphine reagents and opiates was observed at concentrations higher than 120 mg/l morphine, 320 mg/l methadone, 30 mg/l codeine, 60 mg/l dihydrocodeine and 520 mg/l morphine-3-glucuronide. The cross-reactivity with morphine has the greatest impact on routine screening as opiate maintenance therapy in Austria is also performed with slow-release oral morphine. The use of a second… CONTINUE READING

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