Cross-reactivity of anti-Mycobacterium gordonae antibodies with the major mitochondrial autoantigens in primary biliary cirrhosis.

@article{Vilagut1994CrossreactivityOA,
  title={Cross-reactivity of anti-Mycobacterium gordonae antibodies with the major mitochondrial autoantigens in primary biliary cirrhosis.},
  author={L Vilagut and Jordi Vil{\`a} and Octavi Vi{\~n}as and Albert Pares and {\'A}ngels Gin{\'e}s and Mar{\'i}a Teresa Jim{\'e}nez de Anta and J. J. Rodes},
  journal={Journal of hepatology},
  year={1994},
  volume={21 4},
  pages={
          673-7
        }
}
Primary biliary cirrhosis is a chronic cholestatic liver disease associated with autoimmune disorders. Antimitochondrial autoantibodies and granulomatous portal lesions are characteristic in primary biliary cirrhosis. Since granuloma may be induced by Mycobacteria, and there is evidence implicating Mycobacteria as infectious agents capable of initiating autoimmunity, a study was performed to determine the presence of antibodies against 10 atypical Mycobacteria in 19 patients with primary… CONTINUE READING

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