Cross-reactivity between HLA-A2-restricted FLU-M1:58–66 and HIV p17 GAG:77–85 epitopes in HIV-infected and uninfected individuals

@article{Acierno2003CrossreactivityBH,
  title={Cross-reactivity between HLA-A2-restricted FLU-M1:58–66 and HIV p17 GAG:77–85 epitopes in HIV-infected and uninfected individuals},
  author={Paula M Acierno and Danforth A. Newton and Edwin A Brown and Lou Anne Maes and John E. Baatz and Sebastiano Gattoni-Celli},
  journal={Journal of Translational Medicine},
  year={2003},
  volume={1},
  pages={3 - 3}
}
The matrix protein of the influenza A virus and the matrix and capsid proteins of the human immunodeficiency virus (HIV) share striking structural similarities which may have evolutionary and biological significance. These similarities led us to hypothesize the existence of cross-reactivity between HLA-A2-restricted FLU-M1:58–66 and HIV-1 p17 GAG:77–85 epitopes. The hypothesis that these two epitopes are cross-reactive was tested by determining the presence and extent of FLU/GAG immune cross… CONTINUE READING

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