Cross-reactive rubella virus and glutamic acid decarboxylase (65 and 67) protein determinants recognised by T cells of patients with Type I diabetes mellitus

@article{Ou2000CrossreactiveRV,
  title={Cross-reactive rubella virus and glutamic acid decarboxylase (65 and 67) protein determinants recognised by T cells of patients with Type I diabetes mellitus},
  author={Dongmei Ou and Leslie A Mitchell and Daniel L. Metzger and S. Gillam and Aubrey J. Tingle},
  journal={Diabetologia},
  year={2000},
  volume={43},
  pages={750-762}
}
Aims/hypothesis. To examine the cross-reaction between viral and beta-cell protein determinants and to further understand the potential role of this mechanism in Type I (insulind-dependent) diabetes mellitus.¶Methods. Immune responses to a panel of 28 viral and beta-cell protein peptides representing selected sequences of rubella virus (RV), Coxsackie virus, human 38 KDa31G and glutamic acid decarboxylase (GAD 65 and 67) proteins in proliferation or cytotoxicity assays have been studied using… CONTINUE READING
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