Cross-reaction of contraceptive steroids in competitive binding assays of progesterone and estradiol.

@article{Kharma1972CrossreactionOC,
  title={Cross-reaction of contraceptive steroids in competitive binding assays of progesterone and estradiol.},
  author={Khalil M. Kharma and Sergio C. Stone and IanH. Thorneycroft and Robert Nakamura and Daniel R. Mishell},
  journal={American journal of obstetrics and gynecology},
  year={1972},
  volume={112 5},
  pages={
          676-80
        }
}
Cross-reaction of oral contraceptives (OCs) in competitive binding assays of progesterone and estradiol was investigated. The compounds tested were chlormadinone acetate, diethylstilbestrol, dimethisterone, dydrogesterone, ethinyl estradiol, ethynodiol diacetate, megestrol acetate, mestranol, norethynodrel, norethindrone, d-norgestrel, medroxyprogesterone acetate, quinestrol, and quingestanol acetate. Only ethinyl estradiol had a cross-reaction of more than 1% (2%) in the estradiol… CONTINUE READING