Cross-linking of scleral collagen in the rabbit using riboflavin and UVA.

  title={Cross-linking of scleral collagen in the rabbit using riboflavin and UVA.},
  author={Gregor Wollensak and Elena N. Iomdina and D. -D. Dittert and Olga Salamatina and Gisela Stoltenburg},
  journal={Acta ophthalmologica Scandinavica},
  volume={83 4},
PURPOSE Scleral biomechanical weakness and thinning is known to be one of the main factors in the pathogenesis of progressive myopia. We tried to strengthen rabbit sclera by cross-linking scleral collagen using ultraviolet A (UVA) and the photosensitizer riboflavin. METHODS Circumscribed 10 x10 mm sectors of the posterior--equatorial sclera of six chinchilla rabbit eyes were treated in vivo using a UVA double diode with 4.2 mW/cm(2) UVA at 370 nm and applying 0.1% riboflavin-5-phosphate drops… CONTINUE READING
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