Cross-linked electrospun cartilage acellular matrix/poly(caprolactone-co-lactide-co-glycolide) nanofiber as an antiadhesive barrier.

@article{Lee2018CrosslinkedEC,
  title={Cross-linked electrospun cartilage acellular matrix/poly(caprolactone-co-lactide-co-glycolide) nanofiber as an antiadhesive barrier.},
  author={Jin Woo Lee and Joon Yeong Park and Seung Hun Park and Min Ju Kim and Bo Song and Hee-Woong Yun and Tae Woong Kang and Hak Soo Choi and Young Jick Kim and Byoung Hyun Min and Moon Suk Kim},
  journal={Acta biomaterialia},
  year={2018},
  volume={74},
  pages={
          192-206
        }
}
In this work, we chose cartilage acellular matrix (CAM) as a promising antiadhesive material because CAM effectively inhibits the formation of blood vessels, and we used electrospinning to prepare antiadhesive barriers. Additionally, we synthesized N-hydroxysuccinimide (NHS)-poly(caprolactone-co-lactide-co-glycolide)-NHS (MP) copolymers (to tune degradation) as a cross-linking agent for CAM. This is the first report on the development of electrospun cross-linked (Cx) CAM/MP (CA/P) nanofiber (NF… CONTINUE READING