Cross-idiotypic reactions among anti-Rh (D) antibodies.

  title={Cross-idiotypic reactions among anti-Rh (D) antibodies.},
  author={O T Forre and Jacob B. Natvig and T E Michaelsen},
  journal={Scandinavian journal of immunology},
  volume={6 10},
In a series of experiments several idiotype-specific rabbit antisera produced against different IgG anti-Rh (D) antibodies reacted with other anti-Rh (D) antibodies and thus showed cross-idiotypic reactions. Some of the antisera agglutinated almost all types of anti-D-sensitized erythrocytes, whereas other idiotype-specific antisera agglutinated only a few anti-D-sensitized erythrocytes. Anti-D-antibodies showed several different cross-idiotypic reaction patterns. The cross-idiotypic antigens… CONTINUE READING