Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.

@article{Huang2010CrossdisorderGA,
  title={Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.},
  author={Jie Huang and Roy H. Perlis and Phil Hyoun Lee and A. John Rush and Maurizio Fava and Gary S. Sachs and Jeffrey A. Lieberman and Steven P. Hamilton and Patrick Sullivan and Pamela Sklar and Shaun M Purcell and Jordan W. Smoller},
  journal={The American journal of psychiatry},
  year={2010},
  volume={167 10},
  pages={1254-63}
}
OBJECTIVE Family and twin studies indicate substantial overlap of genetic influences on psychotic and mood disorders. Linkage and candidate gene studies have also suggested overlap across schizophrenia, bipolar disorder, and major depressive disorder. The purpose of this study was to apply genomewide association study (GWAS) analysis to address the specificity of genetic effects on these disorders. METHOD The authors combined GWAS data from three large effectiveness studies of schizophrenia… CONTINUE READING
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