Cross-compartment proteostasis regulation during redox imbalance induced ER stress.

Abstract

Imbalance in protein homeostasis in specific subcellular organelles is alleviated through organelle-specific stress response pathways. As a canonical example of stress activated pathway, accumulation of misfolded proteins in ER activates unfolded protein response (UPR) in almost all eukaryotic organisms. However, very little is known about the involvement… (More)
DOI: 10.1002/pmic.201300449

Topics

  • Presentations referencing similar topics