Cross-Study Homogeneity of Psoriasis Gene Expression in Skin across a Large Expression Range

@inproceedings{Bigler2013CrossStudyHO,
  title={Cross-Study Homogeneity of Psoriasis Gene Expression in Skin across a Large Expression Range},
  author={Jeannette Bigler and Hugh A. Rand and Keith Kerkof and Martin S. Timour and Christopher Russell},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND In psoriasis, only limited overlap between sets of genes identified as differentially expressed (psoriatic lesional vs. psoriatic non-lesional) was found using statistical and fold-change cut-offs. To provide a framework for utilizing prior psoriasis data sets we sought to understand the consistency of those sets. METHODOLOGY/PRINCIPAL FINDINGS Microarray expression profiling and qRT-PCR were used to characterize gene expression in PP and PN skin from psoriasis patients. cDNA… CONTINUE READING
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