• Corpus ID: 37147227

Cross-Reactive Inflammation to Milk as a Causal Factor in Acne

  title={Cross-Reactive Inflammation to Milk as a Causal Factor in Acne},
  author={Alan M. Dattner},
Milk consumption was linked to acne on and off for over a century in both the literature and common practice until the advent of tetracycline. During the past decade, milk, whey protein, and especially skim milk have again been linked to acne in a number of epidemiological studies and case reports. This association has been largely attributed to hormone content as well as to insulin increase, IGF-1 and the cascade of responses involving Fox01 and mTORC1 activation. Evidence has accumulated… 



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This new paradigm subverts traditional theories underlying the development of these diseases and suggests that these processes can be arrested if the interplay between genes and environmental triggers is prevented by reestablishing the zonulin-dependent intestinal barrier function.

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A positive association between intake of milk and acne is found and this finding supports earlier studies and suggests that the metabolic effects of milk are sufficient to elicit biological responses in consumers.

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