Cross-Linking and Intracorneal Ring Segments—Review of the Literature

  title={Cross-Linking and Intracorneal Ring Segments—Review of the Literature},
  author={Noa Avni-Zauberman and David S. Rootman},
  journal={Eye \& Contact Lens: Science \& Clinical Practice},
Objectives: To review and summarize relevant studies on combined use of corneal crosslinking and intracorneal ring segments (ICRS) for the treatment of corneal ectasia. Methods: A literature search was performed using the key words “corneal collagen cross-linking” and “intra-corneal ring segments.” Results: Crosslinking is a well-accepted treatment option for corneal ectasia and can be combined with corneal ICRS insertion as needed. The advent of crosslinking has dramatically reduced the number… 
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Keratoconus and Other Corneal Diseases: Pharmacologic Cross-Linking and Future Therapy.
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Intracorneal ring segments in ectatic corneal disease – a review
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Collagen Crosslinking for Keratoconus
This study showed that crosslinking was effective in halting the progression of keratoconus over a period of 4 years, with varying degrees of improvement in visual acuity and reduction in keratometry with a progressive trend in improvement depending on the duration of follow-up.
Intacs with or without same-day corneal collagen cross-linking to treat corneal ectasia.
Intracorneal Ring Segment Explantation After Intracorneal Ring Segment Implantation Combined With Same-Day Corneal Collagen Crosslinking in Keratoconus
Despite the reversal of refractive outcomes, the preservation of topographic changes may occur in some cases after the explantation of 1 or both the segments in patients with keratoconus treated with ICRS implantation with same-day CXL.
Sequential versus concurrent KERARINGS insertion and corneal collagen cross-linking for keratoconus
Combined KERARINGS insertion and CXL can be performed safely in one or two sessions, however, the same-session procedure appears to be more effective regarding the improvement in the corneal shape.
Intracorneal ring segments implantation followed by same-day photorefractive keratectomy and corneal collagen cross-linking in keratoconus.
The combination of intracorneal ring segments implantation followed by sequential same-day PRK/CXL may be a reasonable option for improving visual acuity in select patients with keratoconus.
Corneal Collagen Cross-Linking Before Ferrara Intrastromal Corneal Ring Implantation for the Treatment of Progressive Keratoconus
FR implantation after CXL is a safe and efficacious treatment option for managing selected patients with progressive keratoconus and good results in terms of visual acuity, postoperative residual refractive error, and keratometry values were obtained.