Cross-Correlated Motions in Azidolysozyme

  title={Cross-Correlated Motions in Azidolysozyme},
  author={Seyedeh Maryam Salehi and Markus Meuwly},
The changes in the local and global dynamics of azide-labelled lysozyme compared with that of the wild type protein are quantitatively assessed for all alanine residues along the polypeptide chain. Although attaching -N3 to alanine residues has been considered to be a minimally invasive change in the protein it is found that depending on the location of the alanine residue, the local and global changes in the dynamics differ. For Ala92, the change in the cross-correlated motions are minimal… 

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