• DOI:10.1007/s00384-005-0003-7
Corpus ID: 13271176

Crohn's disease: the cold chain hypothesis

@article{Forbes2005CrohnsDT,
  title={Crohn's disease: the cold chain hypothesis},
  author={A. Forbes and T. Kalantzis},
  journal={International Journal of Colorectal Disease},
  year={2005},
  volume={21},
  pages={399-401}
}

• A. Forbes, T. Kalantzis
• Published 2005
• Medicine
• International Journal of Colorectal Disease

A recent published hypothesis proposed that Crohn's disease was provoked by infantile exposure to micro-organisms that can survive refrigerator temperature. A case–control study was accordingly devised. The mean age at first fridge was 5.6 years amongst 88 patients with Crohn's disease, 5.5 years in 88 patients with ulcerative colitis (UC) and 7.6 years in 88 controls, but a majority of individuals had always been exposed to refrigerated food. Differences were more striking in subjects aged… Expand

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