Crohn's-like changes in the colon due to mycophenolate?

  title={Crohn's-like changes in the colon due to mycophenolate?},
  author={Ignace Dalle and Bart Dirk Maes and Karen Paula Geboes and Wim Lemahieu},
  journal={Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland},
  volume={7 1},
OBJECTIVE Mycophenolate mofetil (MMF) is used for prevention of allograft rejection in kidney transplant patients. A subset of patients suffers from chronic diarrhoea of unknown origin. The aim of the study was to investigate the effect of MMF on the colonic mucosa. MATERIALS AND METHODS Colonic mucosal biopsies from 24 kidney transplant patients receiving MMF and presenting with chronic diarrhoea were analysed using routine stainings and immunohistochemistry for Ki67 and E-cadherin. Results… CONTINUE READING
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