Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene.

@article{Machida2005CrohnsDI,
  title={Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene.},
  author={Haruhisa Machida and Kazuhiro Tsukamoto and Chun-Yang Wen and Saburou Shikuwa and Hajime Isomoto and Yohei Mizuta and Fuminao Takeshima and Kunihiko Murase and Naomichi Matsumoto and Ikuo Murata and Shigeru Kohno and Chen-Yang Wen},
  journal={World journal of gastroenterology},
  year={2005},
  volume={11 31},
  pages={
          4833-7
        }
}
AIM To investigate the frequency and distribution of N-acetyltransferase 2 (NAT2) and uridine 5'-diphosphate (UDP)-glucuronosyltransferase 1A7 (UGT1A7) genes in patients with ulcerative colitis (UC) and Crohn's disease (CD). METHODS Frequencies and distributions of NAT2 and UGT1A7 SNPs as well as their haplotypes were investigated in 95 patients with UC, 60 patients with CD, and 200 gender-matched, unrelated, healthy, control volunteers by PCR-restriction fragment length polymorphism (RFLP… CONTINUE READING
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