Crocetin attenuates atherosclerosis in hyperlipidemic rabbits through inhibition of LDL oxidation.

Abstract

Oxidation of low-density lipoprotein plays a crucial role in the pathogenesis of atherosclerosis, raising the possibility of using antioxidants as an inhibitor of atherosclerosis. However, studies with antioxidants have led to contradictory results. In the present study, we investigated the effect of crocetin, a carotenoid with potent antioxidant activity… (More)

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