Criticality in cell differentiation

@article{Bose2017CriticalityIC,
  title={Criticality in cell differentiation},
  author={Indrani Bose and Mainak Pal},
  journal={Journal of Biosciences},
  year={2017},
  volume={42},
  pages={683-693}
}
Cell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. The differentiation dynamics have both deterministic and stochastic components. Several theoretical studies suggest that cell differentiation is a bifurcation phenomenon, well-known in dynamical systems theory. The bifurcation point has the character of a critical point with the system dynamics exhibiting specific… CONTINUE READING