Critical time periods and the effect of tryptophan in malathion-induced developmental defects in Xenopus embryos.

@article{Snawder1990CriticalTP,
  title={Critical time periods and the effect of tryptophan in malathion-induced developmental defects in Xenopus embryos.},
  author={John E. Snawder and Janice E. Chambers},
  journal={Life sciences},
  year={1990},
  volume={46 23},
  pages={
          1635-42
        }
}
  • John E. Snawder, Janice E. Chambers
  • Published 1990
  • Biology, Medicine
  • Life sciences
  • Xenopus laevis embryos were exposed to the organophosphorus insecticide malathion or its metabolite malaoxon during the first four days of development. The compounds produced the following defects in a dose dependent manner: reduced size, abnormal pigmentation, abnormal gut, enlargement of the atria and aorta, bent notochord and lowered NAD+ levels. Notochords were bent downward between the third and sixth somites with concurrent compression of the somites. Anterior intestine diameter was… CONTINUE READING

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