Critical temperature ranges of hypothermia-induced platelet activation: possible implications for cooling patients in cardiac surgery.

@article{Straub2007CriticalTR,
  title={Critical temperature ranges of hypothermia-induced platelet activation: possible implications for cooling patients in cardiac surgery.},
  author={Pablo A. Straub and Melanie Breuer and Hans Peter Wendel and Karlheinz Dr. Peter and Klaus Dietz and Gerhard Ziemer},
  journal={Thrombosis and haemostasis},
  year={2007},
  volume={97 4},
  pages={
          608-16
        }
}
Cooling of the patient is routinely applied in cardiac surgery to protect organs against ischemia. Hypothermia induces activation of platelets, but the effects of temperatures such as used during cardiac surgery are not well described. To investigate this in an in-vitro study heparinized whole blood was incubated at different temperatures (37 degrees C, 34.5 degrees C, 32 degrees C, 29.5 degrees C, 27 degrees C, 24.5 degrees C, 22 degrees C, 19.5 degrees C and 17 degrees C). The effect of these… CONTINUE READING

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