Critical role of aquaporin-3 in epidermal growth factor-induced migration of colorectal carcinoma cells and its clinical significance.

@article{Li2013CriticalRO,
  title={Critical role of aquaporin-3 in epidermal growth factor-induced migration of colorectal carcinoma cells and its clinical significance.},
  author={Ang Li and De⁃hong Lu and Yupeng Zhang and Jia Li and Yu Fang and Fei Lı and Jia-bang Sun},
  journal={Oncology reports},
  year={2013},
  volume={29 2},
  pages={
          535-40
        }
}
Aquaporins (AQPs) are a family of small, integral membrane proteins that have been shown to play an important role in tumor development and metastasis. Several studies have demonstrated that expression of AQP3 contributes to the enhanced migration of epithelial cells and is related to differentiation, metastasis and vascular invasion in lung and gastric cancer. Therefore, we investigated whether AQP3 could enhance human colorectal carcinoma cell migration and we examined the role of AQP3 in the… 
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