Critical role of TLR2 in triggering protective immunity with cyclophilin entrapped in oligomannose-coated liposomes against Neospora caninum infection in mice.

@article{Fereig2019CriticalRO,
  title={Critical role of TLR2 in triggering protective immunity with cyclophilin entrapped in oligomannose-coated liposomes against Neospora caninum infection in mice.},
  author={Ragab M. Fereig and Hanan H Abdelbaky and Yasuhiro Kuroda and Yoshifumi Nishikawa},
  journal={Vaccine},
  year={2019},
  volume={37 7},
  pages={
          937-944
        }
}
Neospora caninum is an intracellular protozoan parasite closely related to Toxoplasma gondii. N. caninum is thought to be a major cause of abortion in cattle worldwide. Given the current situation of drastic economic losses and a lack of efficient control strategies against such parasites, the challenge to develop potent vaccine candidates and technologies remains. We investigated the immune stimulating activity of N. caninum cyclophilin (NcCyp) with and without a formulation with oligomannose… CONTINUE READING
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