Critical role of IL-21 in modulating TH17 and regulatory T cells in Behçet disease.

@article{Geri2011CriticalRO,
  title={Critical role of IL-21 in modulating TH17 and regulatory T cells in Behçet disease.},
  author={Guillaume Geri and Benjamin Terrier and Michelle Rosenzwajg and Bertrand Wechsler and Maxime Touzot and Danielle Seilhean and T{\'u}-Anh Tran and Bahram Bodaghi and Lucile Musset and Vassili Soumelis and David Klatzmann and Patrice Cacoub and David Saadoun},
  journal={The Journal of allergy and clinical immunology},
  year={2011},
  volume={128 3},
  pages={
          655-64
        }
}
  • Guillaume Geri, Benjamin Terrier, +10 authors David Saadoun
  • Published in
    The Journal of allergy and…
    2011
  • Medicine
  • BACKGROUND Behçet disease (BD) is a chronic systemic inflammatory disorder of unknown etiology. OBJECTIVE To determine the nature of T cells driving inflammatory lesions in BD. METHODS T cell homeostasis and cytokines production were analyzed in peripheral blood and brain inflammatory lesions from 45 adult patients with BD (active and untreated BD [n = 25] and patients in remission [n = 20]) and 20 healthy donors, using Luminex, flow cytometry, immunohistochemistry, and immunofluorescence… CONTINUE READING

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