Critical review of clinical trials in senile dementia

The role of dopamine in behavioural arousal and the frequent occurrence of dementia in patients with Parkinson's disease provide the rationale for the use of these substances in dementia, although dopamine levels in the caudate nucleus and substantia nigra are not depressed in primary degenerative dementia (PDD)56. L-Dopa has yielded contradictory results.6… CONTINUE READING