• DOI:10.1038/nrn1787
Corpus ID: 5264124

Critical period plasticity in local cortical circuits

@article{Hensch2005CriticalPP,
  title={Critical period plasticity in local cortical circuits},
  author={T. Hensch},
  journal={Nature Reviews Neuroscience},
  year={2005},
  volume={6},
  pages={877-888}
}

T. Hensch

Published 2005

Psychology, Medicine

Nature Reviews Neuroscience

Neuronal circuits in the brain are shaped by experience during 'critical periods' in early postnatal life. In the primary visual cortex, this activity-dependent development is triggered by the functional maturation of local inhibitory connections and driven by a specific, late-developing subset of interneurons. Ultimately, the structural consolidation of competing sensory inputs is mediated by a proteolytic reorganization of the extracellular matrix that occurs only during the critical period… CONTINUE READING

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