Critical pathogenic steps to high risk Helicobacter pylori gastritis and gastric carcinogenesis.

@article{Lee2014CriticalPS,
  title={Critical pathogenic steps to high risk Helicobacter pylori gastritis and gastric carcinogenesis.},
  author={Inchul Lee},
  journal={World journal of gastroenterology},
  year={2014},
  volume={20 21},
  pages={6412-9}
}
Helicobacter pylori (H. pylori) gastritis may progress to high risk gastropathy and cancer. However, the pathological progression has not been characterized in detail. H. pylori induce persistent inflammatory infiltration. Neutrophils are unique in that they directly infiltrate into foveolar epithelium aiming the proliferative zone specifically. Neutrophilic proliferative zone foveolitis is a critical pathogenic step in H. pylori gastritis inducing intensive epithelial damage. Epithelial cells… CONTINUE READING
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