Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood.

  title={Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood.},
  author={K Bieback and Susanne Kern and Harald Kl{\"u}ter and H Eichler},
  journal={Stem cells},
  volume={22 4},
Evidence has emerged that mesenchymal stem cells (MSCs) represent a promising population for supporting new clinical concepts in cellular therapy. However, attempts to isolate MSCs from umbilical cord blood (UCB) of full-term deliveries have previously either failed or been characterized by a low yield. We investigated whether cells with MSC characteristics and multi-lineage differentiation potential can be cultivated from UCB of healthy newborns and whether yields might be maximized by optimal… CONTINUE READING
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enchymal stem cells promote engraftment of human umbilical cord blood - derived CD 34 + cells in NOD / SCID mice

YA Romanov, VA Svintsitskaya, VN Smirnov
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