Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood.

@article{Bieback2004CriticalPF,
  title={Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood.},
  author={K Bieback and Susanne Kern and Harald Kl{\"u}ter and H Eichler},
  journal={Stem cells},
  year={2004},
  volume={22 4},
  pages={625-34}
}
Evidence has emerged that mesenchymal stem cells (MSCs) represent a promising population for supporting new clinical concepts in cellular therapy. However, attempts to isolate MSCs from umbilical cord blood (UCB) of full-term deliveries have previously either failed or been characterized by a low yield. We investigated whether cells with MSC characteristics and multi-lineage differentiation potential can be cultivated from UCB of healthy newborns and whether yields might be maximized by optimal… CONTINUE READING
Highly Influential
This paper has highly influenced 30 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 331 extracted citations

“Regenerative Medicine - from Protocol to Patient”

Springer International Publishing • 2011
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 27 references

enchymal stem cells promote engraftment of human umbilical cord blood - derived CD 34 + cells in NOD / SCID mice

YA Romanov, VA Svintsitskaya, VN Smirnov
Exp Hematol • 2002

, liver , and bone marrow

A Muraglia, R Cancedda, R Quarto
2001

Multilineage differentiation activity by cells isolated from umbilical cord blood: expression of bone, fat, and neural markers.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2001

Similar Papers

Loading similar papers…