Critical issues in using the common mixture toxicity models concentration addition or response addition on species sensitivity distributions: a theoretical approach.

@article{Gregorio2013CriticalII,
  title={Critical issues in using the common mixture toxicity models concentration addition or response addition on species sensitivity distributions: a theoretical approach.},
  author={Vincent Gregorio and Nathalie Ch{\`e}vre and Marion Junghans},
  journal={Environmental toxicology and chemistry},
  year={2013},
  volume={32 10},
  pages={2387-95}
}
The risk of chemical mixtures to ecosystems is often assessed by applying the model of concentration addition or response addition combined with species sensitivity distribution (SSD) curves. Mixture effect predictions have been shown to be consistent only when these models are applied for a single species, however, and not with several species simultaneously aggregated to SSDs. The more stringent procedure for mixture risk assessment would hence be to apply first the concentration addition or… CONTINUE READING
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