Critical intracellular O2 in myocardium as determined by 1H nuclear magnetic resonance signal of myoglobin.

@article{Kreutzer1995CriticalIO,
  title={Critical intracellular O2 in myocardium as determined by 1H nuclear magnetic resonance signal of myoglobin.},
  author={Ulrike Kreutzer and Thomas Jue},
  journal={The American journal of physiology},
  year={1995},
  volume={268 4 Pt 2},
  pages={
          H1675-81
        }
}
The 1H nuclear magnetic resonance (NMR) signal of tissue myoglobin has provided an opportunity to determine the critical O2 level in saline-perfused myocardium at room temperature. Above the intracellular PO2 of 4 mmHg, the myocardium exhibits no sign of hypoxia. At 4 mmHg, the rate pressure product (RPP) decreases, and the lactate formation rate, measured enzymatically, increases. However, O2 consumption and the 31P-NMR signal of phosphocreatine level remain relatively constant until the… CONTINUE READING
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